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SurE, survival protein E : ウィキペディア英語版 | SurE, survival protein E
In molecular biology, the protein domain surE refers to survival protein E. It was originally found that cells that did not contain this protein, could not survive in the stationary phase, at above normal temperatures, and in high-salt media. Hence the name, survival protein E. It is a metal ion-dependent phosphatase that is found in bacteria, and eukaryotes. It is an important stress response protein. This domain is found in acid phosphatases ((EC )), 5'-nucleotidases ((EC )), 3'-nucleotidases ((EC )) and exopolyphosphatases ((EC )). ==Interaction with pcm gene== The gene, ''surE'', is part of a bicistronic operon found upstream of the ''pcm'' gene. When mutated, their phenotypes, or physical characteristics, are very similar and indicate that both gene products are important for survival under stressful conditions.
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